CTA-3
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Explore the Latest Data in Advanced RCC Treatment
CTA-4
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Another aRCC Option

See the selected safety profile of another OPDIVO-based combination for advanced RCC.

CTA-5
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Another Advanced RCC Option

Learn more about another OPDIVO-based combination for advanced renal cell carcinoma.

CTA-7

NEW DATA

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Explore the Latest Data in NSCLC
CTA-8
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More NSCLC Indications

See selected safety profiles for other non-small cell lung cancer indications.

CTA-9
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More NSCLC Indications

Learn how OPDIVO and OPDIVO-based combinations treat non-small cell lung cancer.

CTA-13
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More Melanoma Options

Learn more about all melanoma indications.

CTA-14
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More Melanoma Options

See selected safety profiles for other melanoma indications.

CTA-22
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Dosing Schedules

Learn about dosing across all indications.

CTA-23.1
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Dosing Schedules

Find dosing information to get patients started on therapy. 

CTA-23.2
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Dosing Schedules

Find dosing information to get patients started on therapy. 

CTA-23.3
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Dosing Schedules

Find dosing information to get patients started on therapy. 

CTA-23.4
OPDIVO® (nivolumab) vial with timer icon
Dosing Schedules

Find dosing information to get patients started on therapy. 

CTA-23.5
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Dosing Schedules

Find dosing information to get patients started on therapy. 

CTA-24
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Dosing Information

Find the appropriate dosing information for your patients in any approved regimen.

CTA-25
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Preparation and Administration

Find instructions for preparation, administration, infusion, and storage.

CTA-25.1
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Preparation and Administration

Find instructions for preparation, administration, infusion, and storage.

CTA-26
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Treatment Modifications

See recommended dosing modifications for immune-mediated adverse reactions.

CTA-26.1
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Treatment Modifications

See recommended dosing modifications for immune-mediated adverse reactions.

CTA-39
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Patient Monitoring Checklist

A convenient, printable tool to help nurses identify signs and symptoms of immune-mediated adverse reactions. 

CTA-39.1
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Patient Monitoring Checklist

A convenient, printable tool to help nurses identify signs and symptoms of immune-mediated adverse reactions. 

CTA-43
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OPDIVO Dosing Guide

A guide to dosing across all indications.
 

CTA-43.1
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OPDIVO Dosing Guide

A guide to dosing across all indications.
 

CTA-48
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IMAR Guide

A quick reference guide to immune-mediated adverse reactions (IMARs) associated with treatment.

CTA-48.1
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IMAR Guide

A quick reference guide to immune-mediated adverse reactions (IMARs) associated with treatment.

CTA-49
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OPDIVO® (nivolumab) + YERVOY® logo
Dual I-O Therapy Option

See dual I-O treatment results in metastatic melanoma, advanced RCC, and mNSCLC. 

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CTA-50
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Earlier-Stage Treatment Option

Learn more about neoadjuvant use in resectable NSCLC, adjuvant use in UC, melanoma, and EC or GEJC, and perioperative use in NSCLC.

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CTA-51
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Advanced Melanoma Option

Learn about the latest option for patients with unresectable or metastatic melanoma.

CTA-54.1
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More Gastroesophageal Indications

Learn more about other gastroesophageal indications across adjuvant and 1L metastatic settings.

CTA-54.2
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More Gastroesophageal Indications

Learn more about other gastroesophageal indications across adjuvant and 1L metastatic settings.

CTA-55
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More UC Indications

Learn about another urothelial carcinoma indication.

CTA-56
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More UC Indications

See the selected safety profile of another urothelial carcinoma indication.

CTA-59
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1L Unresectable or Metastatic Urothelial Carcinoma Option

OPDIVO, in combination with cisplatin and gemcitabine, is approved for the 1L treatment of adult patients with unresectable or metastatic urothelial carcinoma.

CTA-1
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Explore the Latest Data in Gastroesophageal Cancer Treatment
CTA-26.1
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Treatment Modifications

See recommended dosing modifications for immune-mediated adverse reactions.

CTA-25.1
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Preparation and Administration

Find instructions for preparation, administration, infusion, and storage.

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Patient Monitoring Checklist

A convenient, printable tool to help nurses identify signs and symptoms of immune-mediated adverse reactions.

In Spanish (Español) In Chinese (在普通话)

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National Comprehensive Cancer Network® (NCCN®) Recommendations

An interactive resource that provides the latest NCCN recommendations for nivolumab (OPDIVO) and nivolumab-based combinations.

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Patient Pocket Guide

A guide that includes a compact wallet card and checklist for patients to recognize and report adverse reactions.

In Spanish (Español) In Chinese (在普通话)

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From the OPDIVO Patient Website

The OPDIVO patient website offers a variety of resources and tools to help patients and caregivers better understand and navigate treatment.

CTA-12
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See the Latest Data in Melanoma Treatment
CTA-19
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Explore the Latest Data in UC Treatment
CTA-33
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A NEW I-O Therapy Option

Discover the latest I-O–based combination therapy and how it may add to your therapy options.

CTA-34
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A NEW OPDIVO-Based Option

Discover how the latest OPDIVO-based combination may add to your treatment options.

CTA-46
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Discover Our Latest FDA Approval

Learn about our latest treatment option and explore the data.

CTA-53

NEW

Discover an FDA Approval
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More Advanced RCC Data

See PFS and ORR data for OPDIVO + YERVOY.

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More 1L mNSCLC (PD-L1 ≥1%) Data

See additional OS and response results for OPDIVO + YERVOY.

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More Advanced Melanoma Data

See subgroup analyses and PFS results for OPDIVO + YERVOY.

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NEW DATA

OPDIVO® (nivolumab) + YERVOY® (ipilimumab) + chemotherapy logo
1L r/m NSCLC
(PD-L1 <1% & ≥1%) 

OPDIVO, in combination with YERVOY and 2 cycles of platinum-doublet chemotherapy, is indicated for the first-line treatment of adult patients with metastatic or recurrent non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations.

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1L mNSCLC (PD-L1 ≥1%)

OPDIVO, in combination with YERVOY, is indicated for the first-line treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors express PD-L1 (≥1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations. 

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NOW APPROVED

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Perioperative NSCLC

OPDIVO, in combination with platinum-doublet chemotherapy, is indicated for the neoadjuvant treatment of adult patients with resectable (tumors ≥4 cm or node positive) NSCLC and no known epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) rearrangements, followed by single-agent OPDIVO as adjuvant treatment after surgery.

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NEW DATA

OPDIVO® (nivolumab) + chemotherapy logo
Neoadjuvant Treatment of Resectable NSCLC 

OPDIVO, in combination with platinum-doublet chemotherapy, is indicated as neoadjuvant treatment of adult patients with resectable (tumors ≥4 cm or node positive) non-small cell lung cancer (NSCLC). 

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2L mNSCLC 

OPDIVO is indicated for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) with progression on or after platinum-based chemotherapy. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO. 

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1L Intermediate- or Poor-Risk aRCC

OPDIVO, in combination with YERVOY, is indicated for the first-line treatment of adult patients with intermediate- or poor-risk advanced renal cell carcinoma (aRCC). 

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OPDIVO® (nivolumab) + CABOMETYX (cabozantinib)y logo
1L Advanced RCC

OPDIVO, in combination with cabozantinib, is indicated for the first-line treatment of adult patients with advanced renal cell carcinoma (aRCC).

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NOW APPROVED

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Perioperative NSCLC

OPDIVO, in combination with platinum-doublet chemotherapy, is indicated for the neoadjuvant treatment of adult patients with resectable (tumors ≥4 cm or node positive) NSCLC and no known epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) rearrangements, followed by single-agent OPDIVO as adjuvant treatment after surgery.

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1L Unresectable or Metastatic UC

OPDIVO, in combination with cisplatin and gemcitabine, is indicated for the first-line treatment of adult patients with unresectable or metastatic urothelial carcinoma.

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Adjuvant Treatment of UC

OPDIVO, as a single agent, is indicated for the adjuvant treatment of adult patients with urothelial carcinoma (UC) who are at high risk of recurrence after undergoing radical resection of UC.

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2L Locally Advanced or Metastatic UC

OPDIVO is indicated for the treatment of adult patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy or have disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy.

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NOW APPROVED

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Perioperative NSCLC

OPDIVO, in combination with platinum-doublet chemotherapy, is indicated for the neoadjuvant treatment of adult patients with resectable (tumors ≥4 cm or node positive) NSCLC and no known EGFR mutations or ALK rearrangements, followed by single-agent OPDIVO as adjuvant treatment after surgery.1

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Neoadjuvant treatment of resectable NSCLC

OPDIVO, in combination with platinum-doublet chemotherapy, is indicated as neoadjuvant treatment of adult patients with resectable (tumors ≥4 cm or node positive) non-small cell lung cancer (NSCLC).1

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Adjuvant treatment of UC

OPDIVO, as a single agent, is indicated for the adjuvant treatment of adult patients with urothelial carcinoma (UC) who are at high risk of recurrence after undergoing radical resection of UC.1

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Adjuvant treatment of melanoma

OPDIVO is indicated for the adjuvant treatment of adult and pediatric patients 12 years and older with completely resected Stage IIB, Stage IIC, Stage III, or Stage IV melanoma.1

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Adjuvant treatment of EC or GEJC

OPDIVO is indicated for the adjuvant treatment of completely resected esophageal cancer (EC) or gastroesophageal junction cancer (GEJC) with residual pathologic disease in adult patients who have received neoadjuvant chemoradiotherapy (CRT).1

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Adjuvant Treatment of Melanoma 

OPDIVO is indicated for the adjuvant treatment of adult and pediatric patients 12 years and older with completely resected Stage III or Stage IV melanoma. 

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Adjuvant Treatment of Melanoma 

OPDIVO is indicated for the adjuvant treatment of adult and pediatric patients 12 years and older with completely resected Stage III or Stage IV melanoma. 

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CTA-54

NOW AVAILABLE

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Subcutaneous Injection Treatment Option

OPDIVO QvantigTM (nivolumab + hyaluronidase-nvhy) is now approved as a 3-5 minute subcutaneous injection.

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Adjuvant Treatment of Melanoma 

OPDIVO is indicated for the adjuvant treatment of adult and pediatric patients 12 years and older with completely resected Stage III or Stage IV melanoma.